ABSTRACT
Newly recognized pandemic infectious disease COVID-19 (Corona-virus disease) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This viral infection causes hypercoagulability and inflammation leading to increased incidence of both arterial and venous thrombotic events (VTEs). Therefore, patients infected with this novel virus seem to be at higher risk of thrombotic events (TEs) resulting in thromboembolic diseases, especially stroke and pulmonary embolism, or even cerebral venous sinus thrombosis (CVST). We report a case of 42-year-old female, presented with features of venous thrombotic events (extensive dural venous sinus thrombosis) and was subsequently found to have COVID-19 positive by reverse transcriptase-polymerase chain reaction (RT-PCR) test. The case report indicates CVST might be an unusual manifestation of COVID-19. Cerebral venous sinus thrombosis even presents as an initial symptom of COVID-19 without significant respiratory symptoms. Early diagnosis and treatment with thrombolytic agent in case of SARS-CoV-2 infection result in reduced morbidity and mortality. We recommend further studies to establish SARS-CoV-2 virus (the COVID-19 disease) as a known risk factor for CVST. © 2020 The author (s).
ABSTRACT
Introduction: Novel corona virus (SARS-Coronavirus-2: SARS-CoV-2) which emerged in Wuhan, China, has spread to multiple countries rapidly. Little information is known about nosocomial infections by SARS-CoV-2 in the initial period. As it spreads across the globe, physicians face the challenges of a contagious pandemic including patient isolation and diagnosis. Case Report: We report a case of concurrent meningoencephalitis and COVID-19 infection in a one-year old Bangladeshi patient who was brought a tertiary hospital in Dhaka, Bangladesh due to fever, convulsion and neck stiffness accompanied by unconsciousness later. Computed tomography (CT) SCAN of brain showed excessive encephalopathic change in both cerebral hemispheres with moderate communicating hydrocephalus, suggesting meningoencephalitis. During his hospitalization, he became infected with SARS-CoV-2 which was confirmed by real time polymerase chain reaction (RT-PCR. Conclusion: SARS-CoV-2 can be rapidly transmitted patient-to patient regardless of whether they have symptoms or not. Each hospital must differentiate patients with known or suspected COVID 19 infection from patients with a low probability COVID-19 infection in order to limit direct or indirect transmission. © 2020 The author (s). Published by Zagazig University.
ABSTRACT
Globally, millions of documented SARS-CoV-2 infections with hundreds of thousands of deaths already reported. The majority of the fatal events have been reported in adults older than 70 years and those who have multiple co-morbidities. Despite the misery fatality of the virus, a significant number of peoples recovered from critical conditions also. Mild cases improved significantly with symptomatic management with strict maintenance of isolation. Therefore, many people believed that COVID-19 is a short-term illness, mild cases recovered completely within 2 weeks and severe or critical illness may require 3-6 weeks for complete recovery. However, the latest issue coming forward is delayed recovery in the surviving patients from severe or moderate COVID presenting with multisystem complications. We reported two cases of post COVID complications, newly named as "long COVID syndrome". We described the common symptoms two patients experienced following recovery from acute phase of COVID-19 and how they were managed. We also discussed on the pathogenesis and management plan of common symptoms persisting after recovery of COVID-19.